Investigation of sinonasal microbiome spatial organization in chronic rhinosinusitis
نویسندگان
چکیده
منابع مشابه
Differentially Regulated Host Proteins Associated with Chronic Rhinosinusitis Are Correlated with the Sinonasal Microbiome
The chronic inflammatory nature of chronic rhinosinusitis (CRS) makes it a morbid condition for individuals with the disease and one whose pathogenesis is poorly understood. To date, proteomic approaches have been applied successfully in a handful of CRS studies. In this study we use a multifaceted approach, including proteomics (iTRAQ labeling) and microbiome (bacterial 16S rRNA gene sequencin...
متن کاملComparison of Sinonasal Symptoms in Patients with Nasal Septal Deviation and Patients with Chronic Rhinosinusitis
Introduction: Disorders of the nose and paranasal sinuses are among the most common chronic illnesses. Although considerable progress has been made in the medical and surgical control of these diseases, a large number of questions relating to the diagnosis, evaluation, and treatment of these conditions remain unanswered. The aim of the present study was to evaluate differences in the frequency ...
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Background: Chronic or recurrent rhinosinusitis (CRS) is a disease associated with impaired quality of life and substantial societal costs. Many cases present without a clear underlying cause and despite the lack of etiology current treatment protocols dictate intervention with antibiotics, anti-inflammatory drugs or surgery often with poor long-term outcome. Recent studies indicate that commen...
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Upper airway diseases including allergic rhinitis, chronic rhinosinusitis with or without polyps, and cystic fibrosis are characterized by substantially different inflammatory profiles. Traditionally, studies on the association of specific bacterial patterns with inflammatory profiles of diseases had been dependent on bacterial culturing. In the past 30 years, molecular biology methods have all...
متن کاملComparison of Sinonasal Symptoms in Patients with Nasal Septal Deviation and Patients with Chronic Rhinosinusitis
INTRODUCTION Disorders of the nose and paranasal sinuses are among the most common chronic illnesses. Although considerable progress has been made in the medical and surgical control of these diseases, a large number of questions relating to the diagnosis, evaluation, and treatment of these conditions remain unanswered. The aim of the present study was to evaluate differences in the frequency o...
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ژورنال
عنوان ژورنال: International Forum of Allergy & Rhinology
سال: 2016
ISSN: 2042-6976
DOI: 10.1002/alr.21854